Last updated: October 25, 2026 · By Ronen, Stay Near The Venue
Treatment at MD Anderson Cancer Center often means days or weeks in Houston, so a comfortable, well-connected place to stay really matters. MD Anderson’s main campus sits in the Texas Medical Center, surrounded by hotels that run shuttles, offer patient rates and have kitchen suites for longer stays.
Quick answer: the Rotary House is the only hotel connected to MD Anderson by an enclosed skybridge. Otherwise, choose a Texas Medical Center hotel with a free shuttle (0.3–1 mi away), or a kitchen suite around NRG Park for longer, lower-cost stays.
Top hotel picks at a glance
| Hotel | Location & highlights | |
|---|---|---|
| Rotary House (Jesse H. Jones Rotary House International) | 1600 Holcombe Blvd; owned by MD Anderson and managed by Marriott, with an enclosed… | Check price |
| Houston Marriott Medical Center/Museum District | about 0.3 mi; on the medical-center shuttle route and very close to MD Anderson. | Check price |
| Hampton Inn & Suites Houston Medical Center | 1715 Old Spanish Trail, about 0.9 mi; free shuttle (weekdays 6:15 a.m.–10 p.m., weekends… | Check price |
| DoubleTree by Hilton Houston Medical Center Hotel & Suites | 6800 Main St; free shuttle within 2 miles and suites with full kitchens or… | Check price |
| Home2 Suites by Hilton Houston Medical Center | kitchenette suites with a dishwasher and a free weekday shuttle to nearby hospitals, including… | Check price |
| Residence Inn Houston Medical Center/NRG | 7807 Kirby Dr, about 1.5 mi; free shuttle and full kitchens. | Check price |
| Candlewood Suites Houston Medical Center | 10025 S Main St, about 3 mi; full kitchens and a shuttle – a… | Check price |
Prices change daily – tap “Check price” for live rates on your dates.
This article contains affiliate links. If you book through them we may earn a commission at no extra cost to you. Shuttle schedules, patient rates and parking prices change, so please confirm details with MD Anderson and the hotel before you book.
See hotels near MD Anderson Cancer Center
Hotel map: live prices near MD Anderson Cancer Center
Where MD Anderson is
The Main Building is at 1515 Holcombe Blvd, with the Mays Clinic at 1220 Holcombe Blvd and the Duncan Building at 1155 Pressler St. MD Anderson runs free patient shuttles between its buildings on weekdays (6 a.m.–7 p.m.), and its wayfinding line is 1-877-632-6789.
Because treatment plans can shift, it’s wise to book with free cancellation and to ask each hotel for its medical or MD Anderson patient rate.
Best areas to stay
| Area | Distance to MD Anderson | Best for |
|---|---|---|
| Texas Medical Center core | ~0.3–0.5 mi | Daily treatment, shortest trips |
| East TMC / Old Spanish Trail | ~0.7–1 mi | Suites with kitchens and shuttles, families |
| NRG Park / Kirby Dr | ~1.5–3 mi | Lower prices, extended stays with shuttles |
| Museum District | ~0.5–1.5 mi north | Quieter area near METRORail |
Connected by skybridge
- Rotary House (Jesse H. Jones Rotary House International) – 1600 Holcombe Blvd; owned by MD Anderson and managed by Marriott, with an enclosed skybridge to the hospital and accessible rooms with roll-in showers. Phone 713-790-1600.
With free shuttle
- Houston Marriott Medical Center/Museum District – about 0.3 mi; on the medical-center shuttle route and very close to MD Anderson.
- Hampton Inn & Suites Houston Medical Center – 1715 Old Spanish Trail, about 0.9 mi; free shuttle (weekdays 6:15 a.m.–10 p.m., weekends 10:15 a.m.–5:45 p.m.), breakfast included, and a discounted MD Anderson patient rate.
Extended stay with a kitchen
- DoubleTree by Hilton Houston Medical Center Hotel & Suites – 6800 Main St; free shuttle within 2 miles and suites with full kitchens or kitchenettes.
- Home2 Suites by Hilton Houston Medical Center – kitchenette suites with a dishwasher and a free weekday shuttle to nearby hospitals, including MD Anderson.
- Residence Inn Houston Medical Center/NRG – 7807 Kirby Dr, about 1.5 mi; free shuttle and full kitchens.
Best value
- Candlewood Suites Houston Medical Center – 10025 S Main St, about 3 mi; full kitchens and a shuttle – a budget-friendly base for long treatment stays.
How to choose the right hotel for your stay
The right choice depends on how long you will be in Houston and how mobile the patient is. For short visits or days with many appointments, the skybridge-connected Rotary House or a Texas Medical Center hotel on a shuttle route keeps travel to a minimum. For treatment lasting weeks, a suite with a kitchen lets you control meals and costs, and shuttle hotels a little farther out are often noticeably cheaper.
Getting there, shuttles & parking
- Airports: MD Anderson estimates taxi fares from its campus at about $50 to Bush Intercontinental (IAH) and about $30 to Hobby (HOU).
- Patient Travel Services: 713-745-2300 or 888-848-9992 (weekdays 8 a.m.–5 p.m.) can help with discounted car rentals and flights.
- METRORail Red Line: stops at Dryden/TMC, TMC Transit Center and Smith Lands; $1.25 per ride or $3 for a day pass, paid by tapping a card or phone.
- MD Anderson parking: Garages 2 and 10 cost $5 for up to an hour and $19 maximum per 24 hours; the Mays Clinic/Duncan garage runs $3–13; valet is $20. Prepaid value passes ($52 for $60, or $100 for $115) save money for frequent visits.
- Hotel shuttles: most run within a 2–3 mile radius and many mainly on weekdays – confirm times before you book.
Helpful tips for patients and families
- Ask every hotel for a “medical rate” or MD Anderson patient rate – Joe’s House (joeshouse.org) lists many rates and booking codes.
- For stays longer than a week, a kitchen suite (Home2, Residence Inn, DoubleTree or Candlewood) helps with special diets and costs.
- Buy a parking value pass if you’ll be driving in often.
- The American Cancer Society Hope Lodge Houston (6801 Ardmore St, 713-848-8905) offers free lodging for eligible patients in active cancer treatment and a caregiver, with a referral.
- Keep the hotel shuttle number in your phone – appointments sometimes run late.
Staying in Houston for a long course of visits
Many people travel to Houston for MD Anderson on repeat visits, and the hotel that works for a two-night stay may not suit a month. If you expect to return often or stay for weeks, consider a place where you can cook some meals, wash clothes, and keep medications organized. Ask the hotel whether it offers discounts for longer stays and whether the rate is guaranteed if your plans stretch beyond your first reservation.
It is wise to separate what you must decide now from what can wait. Book the first few nights with flexible cancellation, then adjust when your care team gives you a clearer schedule. Keep a record of each reservation, including the cancellation policy and the hotel’s direct phone number, so that a change in appointments does not leave you scrambling.
Understanding the Texas Medical Center area
MD Anderson sits within the Texas Medical Center, a large concentration of hospitals and research institutions in Houston. The area is busy on weekdays, and the streets can feel confusing for first-time visitors. METRORail’s Red Line serves the medical center area and nearby Hermann Park, and the Houston METRO site lists stops and fares for current information. If you rely on public transit, check the route and the walk from the nearest stop to your building before you commit to a hotel.
Hermann Park, just across from the medical center area, offers a place for a quiet walk when you need time outdoors, and the Houston Zoo is located there as well. Always check opening hours and any admission details on the official sites. Houston can be hot and humid for much of the year, so allow for slower walking, carry water, and plan outdoor time for early or late in the day.
Heat, rain and getting between buildings
The Houston climate affects how you plan a day around appointments. In warmer months, even a short walk can be tiring, so ask the hotel how far it is from the entrance to the shuttle stop or pickup point, and whether the route is shaded or covered. If anyone in your party tires easily, consider a hotel with a shuttle or a very short, direct route over a cheaper room that adds travel time.
Heavy rain can arrive quickly. Keep a compact umbrella in your bag, and allow extra time on wet days for roads that are slower than usual. Inside buildings, air conditioning can be strong, so a light layer is useful even when it is warm outside.
Support for the people traveling with you
Families often arrive tired, anxious, and unsure what to expect. Plan the practical pieces first so that you can focus on each other. Look at where the nearest pharmacy and grocery store are, whether the hotel offers breakfast early enough for morning appointments, and what the options are for rides if you do not have a car.
A caregiver should feel free to rest. If you have the choice, book a room with two beds or a sofa bed so that a companion can sleep properly, and ask about quiet rooms away from elevators. Keep important papers, such as appointment letters and insurance details, in one folder. If you want emotional support or lodging information, ask your care team about resources they recommend, and treat this guide as practical lodging help rather than medical advice.
Questions to ask before you reserve
Before booking, ask the hotel whether it runs a shuttle toward the medical center, how often it operates, and whether it is accessible for wheelchairs or walkers. Ask about early check-in or luggage storage for morning arrivals, and about weekly rates if your stay may run long.
Ask what parking costs per night if you are driving, and whether there are any additional daily fees on top of the room rate. If a room close to the elevator or on a lower floor helps your party, say so when you reserve and again at check-in. Keep the answers in writing with your booking confirmation, so that any change can be settled quickly without long conversations at the front desk when you are already tired from a day of appointments.
Official sources: MD Anderson Cancer Center official website. Check it for current schedules, transport and ticketing before you book.
How we checked this guide
The “Last updated” date at the top of this page is when we last reviewed it end to end.
- Parking rates, shuttle fees and transport times are taken from the port’s, venue’s or operator’s own published pages and from each hotel’s own website — not from aggregator sites.
- Distances and journey times are the figures the venue or transit operator publishes, not our estimates. Where we give a distance, we say what it is measured to.
- Hotel amenities (breakfast, shuttle hours, pet and parking policies) come from each hotel’s own site. These change more often than anything else here, so confirm them when you book.
- Room rates are deliberately not listed anywhere on this site. They move daily, and a price written one month is wrong the next. Our links take you to live pricing instead.
- We have not stayed at every hotel we write about. Where we contacted a property directly, the guide says so and gives the date. Where a figure comes from a third-party report rather than an official source, we say that too.
Found something out of date or wrong? Tell us and we will fix it.
FAQ
Is any hotel connected to MD Anderson?
Yes. The Rotary House is connected to MD Anderson by an enclosed skybridge.
Which hotels near MD Anderson have shuttles?
Many do, including Hampton Inn & Suites Houston Medical Center, DoubleTree Houston Medical Center, Home2 Suites and Residence Inn Medical Center/NRG. Most serve a 2–3 mile radius.
How much is parking at MD Anderson?
Up to $19 per 24 hours in Garages 2 and 10, and $3–13 at the Mays Clinic/Duncan garage.
Can I take the train to MD Anderson?
Yes. The METRORail Red Line stops at Dryden/TMC and TMC Transit Center; a ride costs $1.25.
Is there free lodging for MD Anderson patients?
Hope Lodge Houston offers free lodging to eligible cancer patients in active treatment and a caregiver, by referral.
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Getting there and getting around
Affiliate links: we may earn a commission at no extra cost to you.
We start at the venue and work outward: walking time, shuttle and transit options first, then guest review scores and value for money. Hotels can’t pay to be listed. Some links are affiliate links, so we may earn a small commission at no extra cost to you. Prices and availability change daily, so always check live rates before you book.



